Article 4120

Title of the article

NEAR- AND REMOTE-TERM STRUCTURAL CHANGES OF VEINS AFTER ENDOVASAL LASER COAGULATION BY RADIATION WITH A WAVE LENGTH OF 1910 nm 

Authors

Belyaev Aleksandr Nazarovich, Doctor of medical sciences, professor, head of the sub-department of general surgery named after professor N. I. Atyasov with otorhinolaryngology and maxillofacial surgery courses, Ogarev Mordovia State University (68, Bolshevistskaya street, Saransk, Russia), E-mail: belyaevan@mail.ru
Kostin Sergey Vladimirovich, Candidate of medical sciences, associate professor, sub-department of general surgery named after professor N. I. Atyasov with otorhinolaryngology and maxillofacial surgery courses, Ogarev Mordovia State University (68, Bolshevistskaya street, Saransk, Russia), E-mail: k0stin@mail.ru
Ryabochkina Polina Anatol'evna, Doctor of physical and mathematical sciences, professor, principal researcher, Laboratory of Optical Spectroscopy of Laser Materials, Institute of Physics and Chemistry, Ogarev Mordovia State University (68, Bolshevistskaya street, Saransk, Russia), E-mail: ryabochkina@freemail.mrsu.ru
Khrushchalina Svetlana Aleksandrovna, Candidate of physical and mathematical sciences, senior lecturer, sub-department of general physics, Institute of Physics and Chemistry, Ogarev Mordovia State University (68, Bolshevistskaya street, Saransk, Russia), E-mail: anabel-2005@yandex.ru
Bushukina Ol'ga Sergeevna, Doctor of veterinary sciences, professor, sub-department of morphology, physiology and veterinary pathology, Ogarev Mordovia State University (68, Bolshevistskaya street, Saransk, Russia), E-mail: OSBushukina@ mail.ru 

Index UDK

617-089 

DOI

10.21685/2072-3032-2020-1-4 

Abstract

Background. To evaluate macro and microscopic changes of veins in the immediate and remote period after endovasal laser coagulation using a wavelength of 1910 nm and a power of 3 Watts.
Materials and methods. Experiments on endovasal laser coagulation of subcutaneous veins (EVLC) with analgesia xylazine hydrochloride 20 mg/ml were carried out on 4 sheep (12 saphenous veins of limbs). EVLC was carried out at a rate of 2 mm/sec and a power of 3 Watts. 40 days after EVLC vein excision was performed for histological evaluation.
Results. EVLC with a wavelength of 1910 nm and a power of 3 Watts is sufficient for thermal damage of the vein wall. Histological analysis in the near postcompletion period indicated thermal damage of the vein wall, accompanied by a reduction in the diameter of veins and their clearance, the violation of differentiation of the layers of the venous wall. The study of veins 40 days after coagulation indicates the preservation of thermal disorders with leukocyte infiltration of the wall, the presence of thrombotic masses in their lumen, the growth of connective tissue.
Conclusions. The nearest changes of the venous wall after laser coagulation are accompanied by its thickening against the background of a decrease in the lumen of the veins and their diameter, a violation of the differentiation of the wall layers. Long-term results (after 40 days) indicate the presence of blood clots in the lumen of veins, leukocyte infiltration of the wall and the appearance of granulation tissue, contributing to the subsequent obliteration of veins. 

Key words

laser photocoagulation, the wavelength of 1910 nm, the power, histology 

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References

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Дата создания: 20.05.2020 12:41
Дата обновления: 20.05.2020 13:26